Prof. M Necmettin PAMIRTurkey
Acibadem University, School of Medicine, Istanbul-Turkey
Current Position
2020 to present Emeritus Professor at Department of Neurosurgery, Acıbadem University, School of Medicine
Specialty & Expertise
Skul base, neuro-oncology
About Me
Dr. Pamir was born in Nicosia- Cyprus on December 26th, 1953. He graduated from Istanbul University- Cerrahpaşa Medical School in 1976. He finished his Neurosurgery training at Hacettepe University, Ankara in 1981. From 1984 to 1985 he completed clinical neurosurgical fellowships at Karolinska and Zurich Universities. In 1985 he became Assistant Professor at Hacettepe University School of Medicine-Department of Neurosurgery and in the same year he earned the Associate Professor degree at the same department. In 1986 he was appointed as chairman of Marmara University School of Medicine-Department of Neurosurgery, Istanbul. In 1991 he earned the Professors Degree at the same institution. In 1992 he was appointed as the director of Marmara University Institute of Neurological Sciences. In 1992 he completed skull-base surgery fellowships at Pittsburgh University, Virginia University and George Washington Universities. In 1995 he received Gamma-Knife training at Karolinska University in Stockholm-Sweden. He served as a member of the Marmara University’s Institute of Neurological Sciences Foundation-Board of Trustees, and as the Physician in Chief of Marmara University Hospital. Dr. Pamir has completed his role as Founding President of Acıbadem University, between 2008-2012. 2008-2018 Dr. Pamir served as the chairman of Department of Neurosurgery at Acıbadem University, School of Medicine. Currently he serves as an active member of the same Department.
He also served as the President of Turkish Neurosurgical Society, as a member of Turkish Neurosurgical Society-Training Committee, and as the director of Turkish Neurosurgical Society training course and as a member of the Advisory Board of Turkish Neurosurgical Society. Internationally, he served as a member of the Training Committee of EANS, as a member of the WFNS-Stereotactic Radiosurgery working group, as first a member of the WFNS-Skull Base Surgery study group then as chairman of WFNS- SBSG an executive committee member and as the secretary then president of the Meningiomas and Cerebral Venous System Society, as the president of Academia Eurasiana Neurochirurgica, and as a founding member and secretary- treasurer of World Academy of Neurological Surgery. He is member of German Academy of Neurosurgery. Now he is acting president of World Academy of Neurological Surgery and served as the second President of Turkish Academy of Neurological Surgery. He is Chairman of the Governance and Auditing Committee and board member of EANS. He is on the review board of 9 international journals including Neurosurgery and Acta Neurochirurgica. He organized 15 international and national meetings. He is a member of 18 international and national societies. He is the only Turkish member of American Academy of Neurological Surgery. He has received 11 awards, including Gold Medal of Academia Eurasiana Neurochirurgica. He has given invited lectures in Neurosurgery Departments of 8 international universities. He has 259 international publications, 84 international conferences and invited lectures, 15 instructions at international courses, 84 conferences in Turkish, 4 edited books, 24 book chapters, 176 presentations at international meetings, 107 articles in Turkish Journals and 411 presentations at national meetings. He is married to Feriha Pamir and is a father of three.
Presentation Information
Microsurgical treatment of clinoidal meningiomas
1110 14:10-14:20
AASNS / AANS Joint Session "Spetzler Symposium"/305
Meningiomas that arise at the anterior clinoid process are termed clinoidal meningiomas and are characterized by unique anatomopathologic correlates that result in unique clinical behavior. According to their site of origin, clinoidal meningiomas can be further divided into three subgroups, which also differ in their clinical presentation and surgical outcome. Clinoidal meningiomas are centered on the anterior clinoid process and grow upward with a small pedicle while causing hyperostosis of the anterior clinoid process itself. The optic nerve is frequently compressed and visual symptoms occur early and in most cases. Upon surgical resection, visual symptoms improve in a significant portion of patients. Cavernous sinus invasion is infrequent. With increasing size, however, clinoidal meningiomas tend to invade surrounding neurovascular structures including distal carotid branches, which results in poor surgical outcome. Most clinoidal meningioma cases are managed with surgery where the anterior clinoid process is also removed along with the tumor either with an extradural or an intradural approach. Standard as well as minimal invasive and skull base approaches are advocated by different groups, but the results are comparable. Surgical results are very good in most cases with low mortality and morbidity. Invasion of the internal carotid artery, optic nerve, or distal carotid branches increase the risk of a postoperative residual. Recurrences are observed and usually managed with Gamma-Knife radiosurgery.
Presentation Information
Intraventricular meningiomas
1109 13:40-13:50
AASNS & WANS Joint Seminar/305
Intraventricular localization is a rare anatomical site for meningiomas. We retrospectively reviewed 1591 patients with intracranial meningioma who were surgically treated between September 1986 and July 2024. Twenty-three patients with IVM were identified. The clinical, radiological, surgical, and follow-up records were analyzed. The archival pathologic specimens were reviewed. Tissue microarray blocks were performed from the formalin-fixed, paraffin-embedded samples of all IVM cases, 2 choroid plexus tissue adjacent to the tumors, and 10 extraventricular fibrous meningioma cases selected as control randomly. Immunohistochemical staining with the antibodies S-100, SOX10, NGFR, and OTX2 was performed and İllumina 850K epic methylation array was performed in 7 patients. Surgical complications included hemiparesis in 1 patient (5%), postoperative seizure in 1 patient (5%), sensorial aphasia in 1 patient (5%), and preexisting headache in 1 patient (5%). Seventeen (81%) of the IVMs had grade I pathology and 4 (19%) had grade II pathology. The immunoprofile of IVMs is identical to the immunoprofile of normal choroid plexus epithelium. Transcortical approaches using intraoperative ultrasonography and intraoperative monitoring with avoidance of eloquent cortical areas can achieve good outcomes. Resection of the choroidal attachments should be attempted. Our results indicate that IVMs do not show arachnoid cap cell phenotype and the findings support that IVMs originate from the choroid plexus epithelium or the progenitors of the choroid plexus epithelium.