Dr. Mitchel Stuart BERGERUSA
UCSF Department of Neurological Surgery
October 1, 2020 to present | Professor, Director Brain Tumor Center |
March 1, 1997 - September 30, 2020 | Professor and Chair |
July 1, 1996 - September 30, 1997 | Professor, University of Washington |
Neurological surgery, intraoperative brain mapping.
Mitchel S. Berger M.D. is the Berthold and Belle N. Guggenhime Professor of the Department of Neurological Surgery at the University of California, San Francisco, and Director of UCSF’s Brain Tumor Center. He is currently one of three members of the President’s Cancer Panel, appointed by President Biden to develop the scope of the National Cancer Program.
Dr. Berger is a pioneer of intraoperative brain mapping — a technique used to avoid functional areas of the brain during surgical resection of a tumor. His work has enabled surgeons to perform more extensive resection of tumor with less chance of producing deficits.
Maximizing glioma extent of resection while minimizing morbidity with brain mapping: An update in the molecular era
1108 08:40-08:55
Neuro-oncology/305
The extent of resection for all diffuse gliomas has become critically important. Recent publications have highlighted the role of supratotal resections in both high-grade and low-grade diffuse gliomas. This appears to be irrespective of the molecular status of the glioma. The ability to maximize extent of resection and to do this safely has benefitted dramatically from the use of cortical and subcortical awake and asleep mapping techniques. In the awake setting this can be done with various language paradigms for testing to keep morbidity less than 3%. Subcortical language and motor mapping can be done which has also significantly reduced morbidity to just a few percent in the asleep patient. Advances in the technique with various mapping methods will be highlighted in this study and described in detail. In essence, the development of these techniques has allowed for a much more aggressive resection for minimizing morbidity and numerous examples will be demonstrated along with a review of the literature with regard to extent of resection and outcome for gliomas facilitated by mapping.